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How to use PrEP?

 Pre-exposure prophylaxis (PrEP) is a medication taken by people who are at high risk of contracting HIV to prevent infection. When used consistently, PrEP is highly effective. Here's a guide on how to use PrEP:

1. Consultation with a Healthcare Provider

  • Eligibility Assessment: Before starting PrEP, consult with a healthcare provider to determine if you are a good candidate for the medication. PrEP is recommended for people who are HIV-negative and at high risk of HIV infection, such as those with an HIV-positive partner, those who have multiple sexual partners, or those who use injectable drugs.
  • HIV Testing: You must test negative for HIV before starting PrEP. Your healthcare provider will perform an HIV test to confirm your status.
  • Baseline Tests: Additional tests, such as kidney function tests and screening for sexually transmitted infections (STIs), may be required to ensure PrEP is safe for you.

2. PrEP Medication

  • Types of PrEP: The most common PrEP medications are Truvada (tenofovir disoproxil fumarate/emtricitabine) and Descovy (tenofovir alafenamide/emtricitabine). Your healthcare provider will prescribe the appropriate medication based on your health status and risk factors.
  • Daily Dosage: PrEP is typically taken as a once-daily pill. Consistent daily use is crucial for maximum effectiveness.

3. Adherence to the Medication Schedule

  • Take It Daily: Take PrEP at the same time each day. Set reminders or use a pillbox to help you remember to take it consistently.
  • Missed Doses: If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.
  • Building Protection: PrEP reaches maximum effectiveness after about 7 days of daily use for receptive anal sex and 20 days for receptive vaginal sex. Use condoms or other protective measures during this time.

4. Ongoing Monitoring and Follow-Up

  • Regular HIV Testing: While on PrEP, you’ll need to have an HIV test every 3 months to ensure you remain HIV-negative. This is critical because continuing PrEP if you contract HIV can lead to drug resistance.
  • Kidney Function Monitoring: Your healthcare provider will monitor your kidney function periodically, as PrEP can affect kidney health in some people.
  • STI Screening: Regular screening for other STIs is recommended, as PrEP does not protect against infections other than HIV.

5. Understanding and Managing Side Effects

  • Common Side Effects: Some people may experience mild side effects like nausea, headache, or fatigue when they first start taking PrEP. These usually go away within a few weeks.
  • Serious Side Effects: Although rare, PrEP can cause more serious side effects like kidney issues or bone density loss. Report any unusual symptoms to your healthcare provider immediately.

6. Condom Use

  • Additional Protection: While PrEP is highly effective in preventing HIV, it does not protect against other STIs or pregnancy. Use condoms in combination with PrEP for broader protection.

7. Sexual Health Counseling

  • Risk Reduction: Your healthcare provider or a sexual health counselor can help you with strategies to reduce your overall risk of HIV and other STIs.
  • Discussing PrEP with Partners: Open communication with sexual partners about PrEP use and sexual health is important for mutual protection and trust.

8. Stopping PrEP

  • Consult Before Stopping: If you decide to stop taking PrEP, consult with your healthcare provider first. They can guide you on how to safely discontinue the medication and discuss alternative HIV prevention strategies.
  • Post-Exposure Protection: After stopping PrEP, continue to use other protective measures, like condoms, until you are certain that you are no longer at risk.

9. Traveling with PrEP

  • Plan Ahead: If you’re traveling, ensure you have enough medication for your trip. Carry a prescription or note from your healthcare provider if traveling to countries with restrictions on PrEP.
  • Time Zone Adjustments: If traveling across time zones, adjust your medication schedule to maintain consistent daily dosing.

By following these guidelines and staying in regular contact with your healthcare provider, you can effectively use PrEP to protect yourself from HIV. Consistency and adherence to the prescribed regimen are key to ensuring the highest level of protection.

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